WormMine: ExpressionPattern Expr1297

• Pattern: sma-6 is expressed during embryonic, larval and adult stages. During the early larval stages (L1-L2), sma-6 is extensively expressed in the anterior pharyngeal and distal posterior regions of the animal. Soon afterwards, expression begins in the posterior intestinal nuclei and advances more anteriorly. Expression is seen in the pairs of intestinal nuclei as they divide. Strong expression is seen in the pharyngeal muscles of the anterior and posterior bulbs of the pharynx. Once the intestinal cell divisions are complete, one can see continued expression in the intestinal cells during L2-L3, and later disappearing in these cells. In adults, the staining pattern disappears from the midsections of the animal and persists in the pharyngeal muscles. In males, expression is seen in the tail, as predicted, but the identity of the cells is unclear. sma-6 expression is also observed in late-stage embryos.
• Primary Identifier: Expr1297
• Subcellular Localization: intestinal nuclei

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
posterior region, from rectum to the end	tail		WBbt:0005741
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004860	sma-6	C32D5.2	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002