WormMine: ExpressionPattern Expr1777

• Pattern: CPL-1 was localized in various cells in early to late embryonic stages as well as in the eggshell surrounding the embryos. CPL-1 accumulated in numerous cells during early embryogenesis; however, as embryos progressed through middle and late developmental stages, the CPL-1 protein clustered in gut cells of the embryos at the early L1 stage. In addition, Ce-CPL-1 was present in the hypodermal and cuticular regions in all larval and adult stages, in the pharyngeal lining of all stages, and in the pharyngeal gland of the adult worms only.
• Primary Identifier: Expr1777
• Subcellular Localization: The subcellular localization of the native CPL protein in C. elegans was determined by immunoelectron microscopy staining. In larval and adult stages the native protein was localized in the cuticular region of the worms and on the outer cuticle of the ridge of the annuli. In molting larvae, the protein was localized in both the old and new cuticle. In addition, the protein was localized on the surface of late-stage embryos.

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
Secretory gland cell of the pharynx	Pharyngeal gland cell		WBbt:0005788
The shell or external calcareous covering of an egg	eggshell		WBbt:0005843

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000776	cpl-1	T03E6.7	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003