WormMine: ExpressionPattern Expr719

• Pattern: Fusion gene selectively expressed in a subset of the nervous system and is not expressed at detectable levels in non neural tissues such as muscle hypodermal tissues, gonad and intestine. Expression is observed in both embryonic and postembryonic development. At 44-cell stage, staining seen in a subset of cells, descendants of the AB founder cell which will form the cells of the nervous system. During the proliferation phase, intensity and number of cells increase considerably but it is difficult to identify individual cells. Most of these cells are clustered in the region that give rise to all ganglia in the head and tail region and the ventral nerve cord of the hatched animals. During late embryogenesis the intensity and number of cells expressing the fusion decreases. In L1 larvae, there is weak staining of the neurons in the head, tail and ventral cord but intensity increases greatly during L2-L4. At larval and adult stages, 6 touch receptor neurons (ALML, ALMR, PLML, PLMR, AVM AND PVM) are stained. The axonal processes of the postembryonic touch cells AVM and PVM are weakly stained, the axonal processes of the embryonic touch cells (ALML, ALMR, PLML, PLMR) are intensely stained. The touch neurons stain weakly in L1 larvae, but by L3 these cells are strongly stained. Among the motor neurons of the ventral nerve cord, embryonically generated DA, DB, motor neurons stain weakly in the embryos and larvae but during L3-L4 larval and adult development intense staining of the 38-39 motor neurons, which include the VA and VB classes.
• Primary Identifier: Expr719
• Remark: Reporter gene fusion type not specified. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Neuron class of seven motoneurons that innervate dorsal muscles and have cell bodies in the ventral cord.	DB neuron		WBbt:0005274
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339
Neuron class of eleven motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VB neuron		WBbt:0005336
Neuron class of nine ventral cord motor neuron, innervates dorsal muscle.	DA neuron		WBbt:0005278
Neuron class of one sensory neuron, anterior ventral microtubule cell, touch receptor.	AVM	lineage name: QR.paa	WBbt:0003832
Neuron class of one neuron, posterior ventral microtuble cell, touch receptor.	PVM	lineage name: QL.paa	WBbt:0004086
Anterior lateral microtubule cell, touch receptor	ALML	lineage name: ABarppaappa	WBbt:0003954
Anterior lateral microtubule cell, touch receptor	ALMR	lineage name: ABarpppappa	WBbt:0003953
Posterior lateral microtubule cell, touch receptor	PLML	lineage name: ABplapappppaa	WBbt:0004104
Posterior lateral microtubule cell, touch receptor	PLMR	lineage name: ABprapappppaa	WBbt:0004103

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006528	tba-1	F26E4.8	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003