WormMine: ExpressionPattern Expr9973

• Pattern: Expression of gfp::sem-2 was first detectable in a subset of cells of the E and MS lineages in early gastrulating-stage embryos. The gfp::sem-2 expression persisted through embryonic and larval development in many cell types, including vulval, hypodermal and intestinal cells. gfp::sem-2 expression in the M lineage was first detectable at the 16-M stage in the SM mother cells, M.v(l/r)pa, and remained in both of their daughter cells, M.v(l/r)paa and M.v(l/r)pap. The presence of GFP::SEM-2 in M.v(l/r)pap was transient: GFP::SEM-2 was not detectable after M.v(l/r)pap differentiated into BWMs. However, GFP::SEM-2 persisted in the nuclei of the SM cells and all their descendants until the 8-SM stage, and became undetectable at the 16-SM stage.
• Primary Identifier: Expr9973
• Subcellular Localization: The GFP::SEM-2 protein was nuclear localized, consistent with its predicted role as a transcription factor.

23 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
female genital.	vulva		WBbt:0006748
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
nucleus of pedigree M.vlpaapa	M.vlpaapa nucleus		WBbt:0002213
nucleus of pedigree M.vlpaapp	M.vlpaapp nucleus		WBbt:0002216
nucleus of pedigree M.vrpaapa	M.vrpaapa nucleus		WBbt:0002236
nucleus of pedigree M.vrpaapp	M.vrpaapp nucleus		WBbt:0002239
post-embryonic cell of pedigree M.vlpa	M.vlpa		WBbt:0007183
post-embryonic cell of pedigree M.vrpa	M.vrpa		WBbt:0007196
Post-embryonic cell of pedigree M.vrpap.	M.vrpap	mu_bod	WBbt:0007202
Post-embryonic cell of pedigree M.vlpap.	M.vlpap	mu_bod	WBbt:0007189
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792
A cell that is the E blast cell or is a lineal descendant of E.	E lineage cell		WBbt:0005208
post-embryonic cell of pedigree M.vlpaaaa	M.vlpaaaa		WBbt:0007186
A cell that is the M blast cell or is a lineal descendant of M.	M lineage cell		WBbt:0008439
post-embryonic cell of pedigree M.vrpaaap	M.vrpaaap		WBbt:0007200
post-embryonic cell of pedigree M.vrpaaaa	M.vrpaaaa		WBbt:0007199
post-embryonic cell of pedigree M.vlpaaap	M.vlpaaap		WBbt:0007187
post-embryonic cell of pedigree M.vlpaaa	M.vlpaaa		WBbt:0007185
post-embryonic cell of pedigree M.vrpaa	M.vrpaa		WBbt:0007197
post-embryonic cell of pedigree M.vlpaa	M.vlpaa		WBbt:0007184
post-embryonic cell of pedigree M.vrpaap	M.vrpaap		WBbt:0007201
post-embryonic cell of pedigree M.vrpaaa	M.vrpaaa		WBbt:0007198
post-embryonic cell of pedigree M.vlpaap	M.vlpaap		WBbt:0007188

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004771	sem-2	C32E12.5	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023