WormMine: ExpressionPattern Expr802

• Pattern: ced-1 was expressed at high levels in cells that can function as engulfing cells. Hypodermal cells, and intestinal and pharyngeal muscle cells. The earliest GFP signal observed was in the four intestinal precursor cells in 50 to 100 cell stage embryos. In embryos at the 250-cell stage or older, CED-1::GFP was visible in hypodermal cells, intestinal cells, and the entire pharyngeal primordium. This expression pattern persisted until hatching. During larval development, intestinal cell expression diminished, but expression in hypodermal cells and in all pharyngeal cells remained strong. GFP signal was also observed in body wall and vulval muscles, and in many neurons in the head and ventral nerve cord In L4 larvae and adult hermaphrodites, the strongest CED-1::GFP signal was observed on the surfaces of the gonadal arms.
• Primary Identifier: Expr802
• Subcellular Localization: The GFP signal was localized to cell surfaces in all cells in which expression was detected

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
organ producing either sperm or ova.	gonad		WBbt:0005175
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000415	ced-1	Y47H9C.4	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002