WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  During the L3 and L4 larval stages, PTC-3::GFP was detected during the morphogenesis of the somatic gonad and vulva. Prominent expression was associated with the H-shaped uterine seam cell (utse), which connects the uterus and vulva. During vulval morphogenesis, PTC-3::GFP was also associated with the toroidal vulE, and possibly vulD cells. In addition, expression was detected in the VC4-VC5 neurons of the vulva. PTC-3::GFP expression is highly dynamic. In particular, high levels of PTC-3::GFP were detected in the hypodermis prior to hatching; expression also intensified in the hypodermis prior to each larval molt. PTC-3::GFP was also detected in the excretory duct, which is involved in maintaining ionic and osmotic regulation (Nelson and Riddle, 1984). Primary Identifier  Expr9231
Subcellular Localization  Expression of the ptc-3p::ptc-3::gfp reporter is predominantly associated with polarized epithelial cells at the plasma membrane and in vesicular structures.

9 Anatomy Terms

Definition Name Synonym Primary Identifier
female genital. vulva   WBbt:0006748
Epidermal layer. hypodermis epidermis WBbt:0005733
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles VC4 lineage name: P6.aap WBbt:0004617
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles VC5 lineage name: P7.aap WBbt:0004613
The extracellular sinus formed by the excretory duct and pore cells. Excretory duct   WBbt:0005777
adult vulval toroid cell, E, formed by fusion of precursors of lineage names P6.paal, P6.paar, P6.pppl and P6.pppr. vulE   WBbt:0006767
membranous cell attaches the uterus to the lateral epidermis (seam) and forms a thin laminar process dorsal to the vulva. formed by fusion of eight pi cell progeny and AC. uterine seam cell utse WBbt:0006789
The components of the gonad that are separate from the germline proper. In hermaphrodite, these include five tissues which are all derived from the somatic primordium : the distal tip cells, the gonadal sheath, the spermatheca, the spermatheca-uterine valve (sp-ut) and the uterus. somatic gonad somatic germline WBbt:0005785
adult vulval toroid cell, D, formed by fusion of precursors of lineage names P5.ppp and P7.paa. vulD   WBbt:0006766

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004210 ptc-3 Y110A2AL.8 Caenorhabditis elegans

5 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003