WormMine: ExpressionPattern Expr16529

• Pattern: The rml-3 transcriptional reporter showed specific rml-3 expression in the hypoderm (primarily in the seam cells, and less abundantly in the Hyp7) during larval development, starting from larval L1 through L4 and young adult (24 h post L4) stages. In dauer animals, we observed rml-3 expression predominantly in the hypodermal syncytium as seam cells were dramatically shrunk. The CRISPR GFP knock-in alleles showed identical expression patterns as the transcriptional reporter during late embryonic and larval development, albeit with lower overall fluorescence intensity of the knock- in reporter. In mature adult animals (> 48 h post L4), we observed no detectable rml-3 expression from either transcriptional or endogenous rml-3 knock-in GFP reporters.
• Primary Identifier: Expr16529

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00015781	rml-3	C14F11.6	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A third stage larva specialized for dispersal and long term survival.		dauer larva Ce	WBls:0000032
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023
	At 20 Centigrade: 0-24 hours after L4-adult molt.		newly molted young adult hermaphrodite Ce	WBls:0000063