WormMine: ExpressionPattern Expr12603

• Pattern: sem-2 expression was identified in several early blastomeres and in some neuronal and non-neuronal progenitors. Its expression colocalized with that of sox-2 in a few progenitors. As in vertebrates, sem-2 expression was observed in postmitotic neurons, but in contrast to the broad expression of SoxC genes in vertebrate postmitotic neurons, only a single class of postembryonic neurons expresses sem-2, the RMH class. sem-2 expression in these neurons is observed throughout larval and adult stages. We did not detect any sem-2 expression in the RME neurons themselves, but sem-2 is instead expressed in the progenitor of RMEL/R.
• Primary Identifier: Expr12603

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A blast cell from which a neuron develops.	neuroblast		WBbt:0008594
embryonic cell	ABalaaaarl		WBbt:0005945
Ring motor neuron/interneuron	RMHL	lineage name: G1.l	WBbt:0005011
Ring motor neuron/interneuron	RMHR	lineage name: G1.r	WBbt:0005009
precursor cell destined to divide some time after hatching.	blast cell		WBbt:0006783
Embryonic cell which descends from the same parent cell as a germline blastomere.	somatic blastomere		WBbt:0008447
embryonic cell	ABalaaaarr		WBbt:0006500

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004771	sem-2	C32E12.5	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023