WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  In both males and hermaphrodites, bnc-1 is almost exclusively expressed in VA and VB motorneurons. Weaker expression is also observed in the SABV neuron pair. The protein localizes exclusively to nuclei. bnc-1 expression is initiated around the postembryonic birth of VA and VB MNs at the late first larval (L1) stage and is maintained throughout the life of the animals. A similar expression pattern is observed with successively smaller reporter gene constructs: (1) a fosmid reporter in which bnc-1 is tagged at the C terminus, (2) the aforementioned rescue construct that contains sequences 1.8 kb upstream of the start codon all the way to the stop codon, or (3) a promoter fusion construct that only contains the sequence 1.8 kb upstream of the start codon. Besides VA/VB MNs, bnc-1 is also expressed in the male-specific CP7 MN and CP8 interneuron in the VNC. Primary Identifier  Expr13235
Subcellular Localization  The protein localizes exclusively to nuclei.
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6 Anatomy Terms

Definition Name Synonym Primary Identifier
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles. VA neuron   WBbt:0005339
Neuron class of eleven motoneurons, distributed along the ventral cord, which innervate ventral body muscles. VB neuron   WBbt:0005336
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1 SABVL lineage name: ABplppapaaaa WBbt:0004998
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1 SABVR lineage name: ABprppapaaaa WBbt:0004997
Male specific interneuron, project into preanal ganglion CP8 lineage name: P10.aapp WBbt:0004888
Male specific motor neuron in ventral cord CP7 lineage name: P9.aapp WBbt:0004889

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00044791 bnc-1 F55C5.11 Caenorhabditis elegans

2 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood. larva Ce WBls:0000023