WormMine: ExpressionPattern Expr10629

• Pattern: In mosaic animals, GFP was detected in almost all tissues, including neurons and muscle cells. Transgenes driving GFP expression under the control of the 263-bp promoter sequence used for emc-6 rescue experiments induced lethality and did not transmit GFP expression after one generation. To bypass this technical issue, the authors characterized the expression pattern of the Caenorhabditis briggsae ortholog of emc-6 (Cb-emc-6) in C. elegans. Interestingly, transgenic expression of Cb-emc- 6 was nontoxic in C. elegans. GFP expression was observed in every tissue from the threefold stage to adulthood. Altogether, these results suggest that emc-6 is ubiquitously expressed.
• Primary Identifier: Expr10629
• Subcellular Localization: EMC-6 primarily localize to the ER.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a cellular object that consists of subcellular components, expresses genes or functions.	Cell	Cell type	WBbt:0004017

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00028298	Cbr-emc-6	CBG05942	Caenorhabditis briggsae

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020