WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  GLB-33 is exclusively expressed in the nervous system. The GLB-33 protein was present in a large number of neurons in the head and tail region, the nerve ring, the ventral and dorsal nerve cord, and several lateral nerve cords. However, despite its wide expression in the nervous system, GLB-33 did not seem to be expressed in any of the amphid, cephalic, labial, or phasmid sensory neurons; the typical expression pattern for these neurons was not observed, nor was any overlap seen between GFP-expression and DiI-staining, a compound that selectively stained several amphid and phasmid neurons. This indicates that GLB- 33 is expressed in motor- or interneurons, which are involved in locomotory behaviour or information processing, and not in neurons that sense environmental cues. Primary Identifier  Expr12260
Subcellular Localization  The expression pattern of the reporter was in line with the membrane bound localization of the receptor. The membrane localization of GLB- 33 was confirmed by the transfection of glb-33-gfp in human neuroblastoma SH-SY5Y cells.
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7 Anatomy Terms

Definition Name Synonym Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. nerve ring circumpharyngeal nerve ring WBbt:0006749
neuron making synapse on an effector (muscle, gland). motor neuron motoneuron WBbt:0005409
a bundle of nerve processes that runs along the dorsal mid-line of the animal. dorsal nerve cord dorsal cord WBbt:0006750
  interneuron   WBbt:0005113

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00022284 glb-33 Y75B7AL.1 Caenorhabditis elegans

0 Life Stages