WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  The nhr-239::gfp reporter was weakly expressed in three to four pairs of neurons in the head and a pharyngeal neuron in late stage embryos and all larval and adult stages. One pair of dorsal neurons express nhr-239::gfp very consistently and appear to be sensory, as do one pair of pharyngeal cells that appear to be the MC, NSM or M3 neurons.Faint fluorescence was observed in the pharynx (which may be an artefact), but did not observe nhr-239 expression in other cells at any stage. As expected from the modest expression levels observed in qRT-PCR experiments, fluorescence from the nhr-239::gfp transgene was very faint. While it is possible that the translational fusion did not recapitulate the entire nhr-239 expression pattern, this result suggests that nhr-239 is expressed only in a very limited subset of neurons. nhr-239 transcripts were identified by real-time qRT-PCR at very low levels (no more than 2x10-6 the level of 18 S rRNA standards) and displayed a more complicated pattern, increasing somewhat from embryos to L1, before declining progressively during later larval development. Primary Identifier  Expr10053

10 Anatomy Terms

Definition Name Synonym Primary Identifier
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine. pharynx esophagus WBbt:0003681
Pharyngeal sensory-motorneurons m3R lineage name: ABaraappppp WBbt:0004469
Pharyngeal sensory-motorneurons m3L lineage name: ABaraapappp WBbt:0004471
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron of the pharyngeal nervous system. pharyngeal neuron   WBbt:0005439
Pharyngeal neurosecretory motorneuron, contain serotonin NSML lineage name: ABaraapapaav WBbt:0004457
Pharyngeal neurosecretory motorneuron, contain serotonin NSMR lineage name: ABaraapppaav WBbt:0004446
neuron that senses external stimuli and transduce them to signals internal to the organism. sensory neuron   WBbt:0005759
Pharyngeal neurons that synapse onto marginal cells MCL lineage name: ABalpaaappp WBbt:0004463
Pharyngeal neurons that synapse onto marginal cells MCR lineage name: ABarapaappp WBbt:0004461

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00021848 nhr-239 Y54F10AM.1 Caenorhabditis elegans

2 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood. larva Ce WBls:0000023