WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Transcription was detected as early as 100 min into development in all cells except the germline. Later in embryogenesis, expression was restricted to neurons, epidermal cells, and cells of the pharynx. In adults, expression was found in head and tail neurons and in neurons along the body, in addition to strong expression in the pharynx and spermatheca. Primary Identifier  Expr11575
Remark  Temporal description Subcellular Localization  A translational fusion protein had the following subcellular localization. In embryos, SRGP-1::GFP localized specifically to sites of contact between cells. When first detected, approximately 150 min after first cleavage, SRGP-1::GFP appeared along most cell-cell contacts. After epidermal differentiation, SRGP-1 appeared uniformly along all apical junctions, where it colocalized with cadherin complex components. SRGP-1 did not colocalize appreciably with DLG-1/discs large and AJM-1, but appeared to reside predominantly apical to the DLG-1-AJM-1 complex. Immunostaining of endogenous SRGP-1 with a polyclonal antibody validated the observations made with the GFP-tagged protein.
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7 Anatomy Terms

Definition Name Synonym Primary Identifier
an accordion-like tube that contains sperm and is the site of oocyte fertilization. spermatheca   WBbt:0005319
Epidermal layer. hypodermis epidermis WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine. pharynx esophagus WBbt:0003681
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. neuron neurone WBbt:0003679
Nucleated cell which has a diploid set of chromosomes. somatic cell FMA:72300 WBbt:0008378

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006406 srgp-1 F12F6.5 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  All C. elegans development stages, including embryo, larva and adult stage. all stages Ce WBls:0000002