WormMine: ExpressionPattern Expr13831

• Pattern: hlh-3 is expressed in the HSN at L4 coinciding with the onset of differentiation. hlh-3 is also expressed in other neurons, including the NSM serotonergic neuron, but not in the ADF serotonergic neuron. hlh-3 is expressed embryonically. HLH-3 shows two waves of expression: it is present in the mother cell of HSN (around 80 minutes of embryonic development) and its expression becomes fainter in postmitotic HSN andPHB neurons. At first larval stage HLH-3 expression isundetectable in HSN and expression reappears at third larval stage, preceding AST-1 onset of expression and HSN maturation and is quickly downregulated at the end of L4. HLH-3 expression is not observed after larval L4 stage.
• Primary Identifier: Expr13831

9 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNL	lineage name: ABplapppappa	WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNR	lineage name: ABprapppappa	WBbt:0004757
Amphid neuron, prob. chemosensory	ADFL	lineage name: ABalpppppaa	WBbt:0004003
Amphid neuron, prob. chemosensory	ADFR	lineage name: ABpraaappaa	WBbt:0003999
Pharyngeal neurosecretory motorneuron, contain serotonin	NSML	lineage name: ABaraapapaav	WBbt:0004457
Pharyngeal neurosecretory motorneuron, contain serotonin	NSMR	lineage name: ABaraapppaav	WBbt:0004446
embryonic cell	ABplapppapp		WBbt:0005970
embryonic cell	ABprapppapp		WBbt:0006743

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001950	hlh-3	T24B8.6	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The time period encompassing the 80th minute post first cleavage at 20 Centigrade with respect to Sulston's lineage tree.		80 min post first-cleavage Ce	WBls:0000191