WormMine: ExpressionPattern Expr8545

• Pattern: The earliest appearance of SEPA-1::GFP was in ~16-cell stage embryos, where it was diffusely distributed in the cytoplasm of almost all cells, with a few small aggregates. SEPA-1::GFP formed aggregates in a temporal pattern similar to that shown by the anti-SEPA-1 antibody. Diffuse SEPA-1::GFP signal was still evident in most cells at the comma stage and was greatly diminished by the 2-fold stage of embryogenesis. After hatching, cytoplasmic SEPA-1 aggregates were found in a few unidentified cells in the head and tail regions and also in the intestine, especially in the anterior and posterior pairs of intestine cells.
• Primary Identifier: Expr8545
• Remark: Picture: Figure 4.
• Subcellular Localization: Diffusely distributed in the cytoplasm of almost all cells, with a few small aggregates.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
posterior region, from rectum to the end	tail		WBbt:0005741
anterior-most body region containing the pharynx.	head		WBbt:0005739

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010808	sepa-1	M01E5.6	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over.		elongating embryo Ce	WBls:0000015
	The C. elegans life stage spanning 0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage until cleavage is over.		proliferating embryo Ce	WBls:0000004