WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  First detected at comma stage in pharyngeal primordium as pharyngeal muscles begin terminal differentiation. Strong expression is detected in most cells during late embryogenesis when cells are either differentiating or undergoing cell cycle arrest prior to hatching. At hatching and in L1 animals maintained in absence of food expression detected in Q, M, Z1, Z4 and V cells. Expression in these cells fades after feeding when cell division resumes. Strong expression is observed in many postmitotic neurons and muscle cells. Stronger expression is detected in newly differentiated cells and then gradually decreases. cki-1 also expressed in dauer larvae. 1. Lateral hyodermal V lineage: V cells show strong expression until they divide in the mid L1 (fluorescence decreases significantly). Seam cells express at quite high levels during resting phases between molts and at a reduced level during division. Expression increases at L4 (coincident with seam cell terminal differentiation). 2. sex myoblasts (SM)lineage: High level of expression observed during SM migration, reduced during SM division and high again as the sex muscles differentiate. 3. P lineage: L1-molt progeny of Pn.a neuroblasts express high levels of cki-1::gfp. 4. Somatic gonad: Expression in Z1 and Z4 diminishes prior to cell division in mid-L1. Strong expression in Z1.aa and Z4.pp, the distal tip cells, beginning in L2, undetectable in the rest of Z1/Z4 lineage until the late L3 and early L4. Expression in somatic gonad increases dramatically at the onset of terminal differentiation. 5. Intestine: After L1-molt expression in intestine is seen throughout the larval stages 6. Vulva precursor cells: cki-1::gfp expression first detected in vulva precursor cells (VPCs) in late L1 or early L2 and peaks at L2 molt. Primary Identifier  Expr608
Remark  In the absence of food expression is very high in arrested larvae and then fades by 8-12h post-feeding. See Table 2 in the article cgc3201 for the stage/tissue type expression patterns of this locus. Lineage expression: SM lineage. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).
Paste the following link
Lists
This ExpressionPattern isn't in any lists. Upload a list.

42 Anatomy Terms

Definition Name Synonym Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages. intestine gut WBbt:0005772
type of cells that make up muscle layers in the pharynx. pharyngeal muscle cell   WBbt:0005451
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad posterior distal tip cell gon herm dtc P WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad anterior distal tip cell gon herm dtc A WBbt:0004520
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail seam cell lateral hypodermis WBbt:0005753
descendent cell of post-embryonic blast cell P5, posterior, in hermaphrodite. P5.p hermaphrodite   WBbt:0008121
descendent cell of post-embryonic blast cell P4, posterior, in hermaphrodite. P4.p hermaphrodite   WBbt:0008117
descendent cell of post-embryonic blast cell P3, posterior in hermaphrodite. P3.p hermaphrodite   WBbt:0008112
  P8.p hermaphrodite   WBbt:0008133
  P7.p hermaphrodite   WBbt:0008129
  P6.p hermaphrodite   WBbt:0008125
Postembryonic neuroblast, migrates posteriorly. QL lineage name: ABplapapaaa WBbt:0004056
Somatic gonad precursor cell Z1 lineage name: MSpppaap WBbt:0004577
Somatic gonad precursor cell Z4 lineage name: MSappaap WBbt:0004574
Postembryonic neuroblast, migrates anteriorly. QR lineage name: ABprapapaaa WBbt:0004054
descendent cell of P2, anterior P2.a   WBbt:0006878
descendent cell of P1, anterior P1.a   WBbt:0006877
descendent cell of P6, anterior P6.a   WBbt:0006882
descendent cell of P5, anterior P5.a   WBbt:0006881
descendent cell of P4, anterior P4.a   WBbt:0006880
descendent cell of P3, anterior P3.a   WBbt:0006879
descendent cell of P10, anterior P10.a   WBbt:0006886
descendent cell of P9, anterior P9.a   WBbt:0006885
descendent cell of P8, anterior P8.a   WBbt:0006884
descendent cell of P7, anterior P7.a   WBbt:0006883
descendent cell of P12, anterior P12.a   WBbt:0006888
descendent cell of P11, anterior P11.a   WBbt:0006887
Seam hypodermal cell, postembryonic blast cell V4L lineage name: ABarppappa WBbt:0004894
Seam hypodermal cell, postembryonic blast cell V4R lineage name: ABarpppppa WBbt:0004892
Seam hypodermal cell, postembryonic blast cell V5L lineage name: ABplapapaap WBbt:0004890

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000516 cki-1 T05A6.1 Caenorhabditis elegans

7 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  A third stage larva specialized for dispersal and long term survival. dauer larva Ce WBls:0000032
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003