WormMine: ExpressionPattern Expr1853

• Pattern: During larval development, tlp-1::gfp expressed in the posterior intestinal cells, several neuronal nuclei in the head, the tail tip cells in hermaphrodites and males and in descendants of the T cell lineage. Weak GFP expression observed in the T cell in 6% (n=124) of animals. After the division of the T cell, stronger GFP expression was observed in the posterior T cell daughter, T.p. but not in T.a. More specifically, of the animals that showed GFP expression in the T cell lineage (57/150), 88% of the animals examined showed GFP expression in T.p alone and 12% showed expression in T.a and T.p. GFP expression was also observed in the posterior T.ap daughter cell, T.app but not in T.ap or its anterior daughter cell T.apa. Specifically, all of the animals that showed expression in the T.ap lineage (11/56) showed GFP expression in T.app alone. No expression observed in T.apa in any animals. tlp-1::gfp expression begins to be barely detectable at the beginning of gastrulation at about 100 minutes of embryonic development. Shortly after the gastrulation begins, the level of expression increases and is detectable in the nuclei of most embryonic cells. This pattern appears to persist through gastrulation. However, at about 260 minutes, expression in the anterior of the embryo fades and expression in the posterior of the embryo persists and gets stronger. At the 1.5-fold stage, at about 400 minutes, expression was observed in posterior nuclei and this pattern continues throughout the rest of development.
• Primary Identifier: Expr1853
• Subcellular Localization: nuclei

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1	TL	lineage name: ABplappppp	WBbt:0004946
Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1	TR	lineage name: ABprappppp	WBbt:0004944
cell, which is the posterior descendent of TR.	TR.p		WBbt:0006997
cell, which is the posterior descendent of TL.	TL.p		WBbt:0006996
Used during embryogenesis to make tail spike, then die	spike precursor right	lineage name: ABprppppppa	WBbt:0004512
Used during embryogenesis to make tail spike, then die	spike precursor left	lineage name: ABplppppppa	WBbt:0004513
cell, which is the posterior descendent of TR.ap.	TR.app		WBbt:0007015
cell, which is the posterior descendent of TL.ap.	TL.app		WBbt:0007011

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006580	tlp-1	T23G4.1	Caenorhabditis elegans

9 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over.		elongating embryo Ce	WBls:0000015
	The C. elegans life stage spanning 290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastrulation and is enclosing.		enclosing embryo Ce	WBls:0000013
	The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation.		gastrulating embryo Ce	WBls:0000010