WormMine: ExpressionPattern Expr9345

• Pattern: mom-2 has previously been reported to be widely expressed along the anteroposterior axis of developing larvae, with expression in body wall muscle cells, ventral cord neurons, intestinal cells and seam cells (Gleason et al., 2006). By contrast, we found that mom- 2 shows a restricted expression pattern, with mom-2 transcripts localizing only to the germ cell precursors Z2 and Z3, their descendants and a few unidentified cells in the tail. mom-2 expression in the germ cells continued throughout larval development, whereas the tail expression reached a maximum at the mid-L1 stage and disappeared before the L1 to L2 molt. In addition, one or two mom-2 transcripts were occasionally detected in posterior seam cells in early L1 larvae. Consistent with the early embryonic function of mom-2 (Thorpe et al., 1997), we found that mom-2 transcripts were already present in the zygote. At the four-cell stage, mom-2 transcripts were enriched in the P2 blastomere. During later stages of embryonic development, mom- 2 transcripts were restricted to the posterior, with expression remaining in the tail and in the region of the Z2 and Z3 germ line precursors in comma stage embryos.
• Primary Identifier: Expr9345

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
posterior region, from rectum to the end	tail		WBbt:0005741
Germ line precursor cell	Z3	lineage name: P4.a	WBbt:0004575
Germ line precursor cell	Z2	lineage name: P4.p	WBbt:0004576
a cell, of either sex, directly concerned in the production of a new organism.	germ cell		WBbt:0006796

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003395	mom-2	F38E1.7	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003