WormMine: ExpressionPattern Expr713

• Pattern: First detected at low levels in some 1-cell embryos. At the 2-cell stage higher level of expression detected predominantly in germline blastomere P1. Distribution of POS-1 protein is similar to distribution of mRNA after 2-cell stage when P1 divides. POS-1 protein is initially present at equal levels in both P1 daughters but persists at higher level only in germline daughter P2. After the division of the final germline blastomere P4, POS-1 is not detected in any cell. POS-1 shows strong, specific staining of granules within the cytoplasm of germline blastomeres. In double labeling experiments with an Ab specific for P granules determined that POS-1 is associated with cytoplasmic and perinuclear P granules. Although P granules is present in germline at all stages of embryonic and postembryonic development, POS-1 staining is only seen in P granules in germline blastomeres, P1, P2, P3 and P4. POS-1 gene is expressed maternally, POS-1 is cytoplasmic, P granule associated protein is present predominantly in germline blastomeres during early embryogenesis.
• Primary Identifier: Expr713
• Remark: This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).
• Subcellular Localization: POS-1 is cytoplasmic.

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
organ producing either sperm or ova.	gonad		WBbt:0005175
The fourth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P4		WBbt:0006773
embryonic founder cell	Psub3	lineage name: P0.ppp	WBbt:0006875
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874
embryonic founder cell	Psub2	lineage name: P0.pp	WBbt:0006873
embryonic cell	EMS		WBbt:0006876
Embryonic founder cell	AB	AB blastomere	WBbt:0004015

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004078	pos-1	F52E1.1	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005