WormMine: ExpressionPattern Expr1516

• Pattern: About 8 hour after hatching, P cells descend into the ventral nerve cord and interdigitate to form a single row of cells of P1-P12. In both sexes, mab-5 was detected in P7-P10. In older larva, mab-5 was detected in P7-P12, but not more anterior cells. In hermaphrodites, expression pattern was similar to males with two exceptions. The p(9-11).app cells and p(9-11).p cells no longer express MAB-5 by L2. In male, descendants of P10 consistently express high levels of MAB-5, those of P9 and P11 express low levels, and those of P7 and P8 express barely detectable levels. P12 descendants express MAB-5 only until the division of P12.a. The descendants of P cells express comparable levels of MAB-5 with exceptions to Pn.p cells, they express lower levels than their neighbors. Expression levels in P descendants were similar to those seen in the neighboring juvenile motoneurons. Both sets of cells expressed MAB-5 in a graded pattern, tapering off toward the anterior. In newly hatched larva, in both sexes, mab-5 was detected consistently in nuclei of P9/10 and P11/12, but not more anterior P cells. mab-5 was also detected at high levels in the posterior juvenile motoneurons, located ventrally. MAB-5 is localized to the posterior of the body, including P7-P12 in the P lineage but not in more anterior cells. Within P7-P12, MAB-5 expression was graded with the highest levels in the P10 descendants. The descendants of any one P cell expressed comparable levels of MAB-5.
• Primary Identifier: Expr1516

77 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles	VC5	lineage name: P7.aap	WBbt:0004613
neuron making synapse on an effector (muscle, gland).	motor neuron	motoneuron	WBbt:0005409
	P8.p hermaphrodite		WBbt:0008133
	P7.p hermaphrodite		WBbt:0008129
descendent cell of P11, posterior	P11.p		WBbt:0006899
descendent cell of P10, posterior	P10.p		WBbt:0006898
Posterior descendent cell of P9 fuses into postembryonic large hypodermal syncytium hyp7.	P9.p		WBbt:0006897
descendent cell of P12, posterior	P12.p		WBbt:0006900
The tenth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P10		WBbt:0006779
The ninth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P9		WBbt:0006778
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P11	lineage name: ABplapappa	WBbt:0004410
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P12	lineage name: ABprapappa	WBbt:0004409
Posterior daughter cell of P8.p, fuses into postembryonic large hypodermal syncytium in hermaphrodite.	P8.pp	lineage name: P8.pp	WBbt:0004145
Anterior daughter cell of P8.p, fuses into postembryonic large hypodermal syncytium in hermaphrodite.	P8.pa	lineage name: P8.pa	WBbt:0004147
Anterior daughter cell of P7.pa, fuses into hermaphrodite vulD syncytium.	P7.paa	lineage name: P7.paa	WBbt:0004448
cell, posterior descendent of P7.p	P7.pp		WBbt:0006984
cell, anterior descendent of P7.p	P7.pa		WBbt:0006983
post-embryonic cell of pedigree P7.ppa	P7.ppa		WBbt:0007265
post-embryonic cell of pedigree P7.pap	P7.pap		WBbt:0007264
post-embryonic cell of pedigree P7.ppp	P7.ppp		WBbt:0007266
The eighth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P8		WBbt:0006777
The seventh (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P7		WBbt:0006776
	P8.p male	hyp7	WBbt:0008132
	P7.p male	hyp7	WBbt:0008128
descendent cell of P10, anterior	P10.a		WBbt:0006886
descendent cell of P9, anterior	P9.a		WBbt:0006885
descendent cell of P8, anterior	P8.a		WBbt:0006884
descendent cell of P7, anterior	P7.a		WBbt:0006883
descendent cell of P12, anterior	P12.a		WBbt:0006888
descendent cell of P11, anterior	P11.a		WBbt:0006887

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003102	mab-5	C08C3.3	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developemental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until death.		postembryonic Ce	WBls:0000022