| Algorithm | Over and under-representation analysis (ORA) and GSEA were performed using web-based tool GeneTrail. Significance cutoff P < 0.05) was determined by a hypergeometric distribution test using all C. elegans genes as background with a 5% FDR multiple testing correction. Genes with a 1.3-fold change in daf-2(e1370) mutants relative to wild type were included in the analysis. The results of the ORA were subsequently confirmed by GSEA, a method that is independent of any fold change cutoff. | Description | Proteins related to protein metabolism that, compared with N2, display reduced abundance in the daf-2(e1370) proteome, and are suppressed by daf-16. |
| Primary Identifier | WBPaper00042552:daf-2(e1370)_downregulated_daf-16-dependent |
| Remark | Definition | Other Name | Public Name | Primary Identifier |
|---|---|---|---|---|
| At 20 Centigrade: 24-48 hours after L4-adult molt. 4-5 days after first cleavage. | 1-day post-L4 adult hermaphrodite Ce | WBls:0000064 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000898 | daf-2 | Y55D5A.5 | Caenorhabditis elegans |
| WBGene00000912 | daf-16 | R13H8.1 | Caenorhabditis elegans |
