WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0006924 activation-induced cell death of T cells GO

Namespace  biological_process Obsolete  false
Description  A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

31 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0022607 cellular component assembly The aggregation, arrangement and bonding together of a cellular component.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state.
GO:0097190 apoptotic signaling pathway The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
GO:0048871 multicellular organismal-level homeostasis Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.
GO:0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
GO:0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
GO:0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0043029 T cell homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0071887 leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0120031 plasma membrane bounded cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0097194 execution phase of apoptosis A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0030031 cell projection assembly Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0032060 bleb assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
GO:0070227 lymphocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0006924 activation-induced cell death of T cells A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0043029 GO:0006924
is_a GO:0070231 GO:0006924
part of GO:0002260 GO:0006924
is_a GO:0071887 GO:0006924
has part GO:0032060 GO:0006924
has part GO:0008150 GO:0006924
has part GO:0071840 GO:0006924
has part GO:0050789 GO:0006924
has part GO:0009987 GO:0006924
part of GO:0042592 GO:0006924
part of GO:0048871 GO:0006924
part of GO:0048872 GO:0006924
part of GO:0008150 GO:0006924
has part GO:0007165 GO:0006924
part of GO:0002376 GO:0006924
is_a GO:0070227 GO:0006924
part of GO:0032501 GO:0006924
has part GO:0022607 GO:0006924
is_a GO:0006915 GO:0006924
has part GO:0016043 GO:0006924
has part GO:0120036 GO:0006924
has part GO:0050794 GO:0006924
is_a GO:0008219 GO:0006924
has part GO:0120031 GO:0006924
is_a GO:0009987 GO:0006924
has part GO:0097194 GO:0006924
has part GO:0097190 GO:0006924
has part GO:0030031 GO:0006924
part of GO:0001776 GO:0006924
has part GO:0030030 GO:0006924

6 Synonyms

Name Type
activation-induced cell death of T-lymphocytes synonym
activation-induced cell death of T lymphocytes synonym
AICD synonym
activation-induced cell death of T-cells synonym
activated T cell apoptosis synonym
antigen-driven apoptosis synonym