WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0097194 execution phase of apoptosis GO

Namespace  biological_process Obsolete  false
Description  A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

7 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  involved_in
  involved_in
has_participant(WB:WBGene00001130) involved_in
has_participant(WB:WBGene00013354) involved_in
has_participant(WB:WBGene00004927) involved_in
  involved_in

14 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0022607 cellular component assembly The aggregation, arrangement and bonding together of a cellular component.
GO:0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
GO:0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0120031 plasma membrane bounded cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0097194 execution phase of apoptosis A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0030031 cell projection assembly Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0032060 bleb assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.

114 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0097194 GO:0001781
has part GO:0097194 GO:0001783
has part GO:0097194 GO:0002342
has part GO:0097194 GO:0002454
has part GO:0097194 GO:0002516
has part GO:0097194 GO:0002901
has part GO:0097194 GO:0003275
has part GO:0097194 GO:0003276
has part GO:0097194 GO:0003277
has part GO:0097194 GO:0003278
has part GO:0097194 GO:0003296
part of GO:0097194 GO:0006309
has part GO:0097194 GO:0006915
part of GO:0097194 GO:0006921
part of GO:0097194 GO:0006921
has part GO:0097194 GO:0006924
has part GO:0097194 GO:0006925
has part GO:0097194 GO:0010657
has part GO:0097194 GO:0010658
has part GO:0097194 GO:0010659
part of GO:0097194 GO:0030262
part of GO:0097194 GO:0030263
part of GO:0097194 GO:0030264
has part GO:0097194 GO:0033024
has part GO:0097194 GO:0033028
has part GO:0097194 GO:0034349
has part GO:0097194 GO:0034390
has part GO:0097194 GO:0043276
has part GO:0097194 GO:0044346
has part GO:0097194 GO:0045476

2 Synonyms

Name Type
apoptosis synonym
execution phase of apoptotic process synonym