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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0051179
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localization
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Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. |
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GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
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GO:0071840
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cellular component organization or biogenesis
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A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
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GO:0016043
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cellular component organization
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A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
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GO:0005215
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transporter activity
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Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. |
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GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
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GO:0051234
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establishment of localization
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Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
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GO:0006810
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transport
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The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0061024
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membrane organization
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A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. |
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GO:0065008
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regulation of biological quality
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Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. |
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GO:0015748
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organophosphate ester transport
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The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. |
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GO:0010256
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endomembrane system organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. |
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GO:0007009
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plasma membrane organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. |
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GO:0010876
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lipid localization
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Any process in which a lipid is transported to, or maintained in, a specific location. |
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GO:0006869
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lipid transport
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The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
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GO:0033036
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macromolecule localization
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Any process in which a macromolecule is transported to, or maintained in, a specific location. |
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GO:0006915
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apoptotic process
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A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
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GO:0097194
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execution phase of apoptosis
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A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
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GO:0008219
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cell death
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Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). |
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GO:0012501
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programmed cell death
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A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. |
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GO:0005319
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lipid transporter activity
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Enables the directed movement of lipids into, out of or within a cell, or between cells. |
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GO:0005548
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phospholipid transporter activity
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Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. |
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GO:0015914
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phospholipid transport
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The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. |
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GO:0097035
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regulation of membrane lipid distribution
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Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane. |
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GO:0140303
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intramembrane lipid transporter activity
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Enables the transport of a lipid from a region of a membrane to a different region on the same membrane. |
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GO:0034204
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lipid translocation
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The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
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GO:0045332
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phospholipid translocation
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The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. |
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GO:0017121
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plasma membrane phospholipid scrambling
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The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). |
