WormMine: ExpressionPattern Expr9921

• Pattern: In worms expressing cbs-1::GFP, the GFP signal was observed in the hypodermis, intestine, body wall muscle cells and pharyngeal muscles pm3, pm4, pm5, pm6, pm7, and pm8 in all larval stages as well as in adults. We did not observe a GFP signal in embryos, although previous transcriptional screens and peptide mapping studies have reported expression of cbs-1 in this developmental stage.
• Primary Identifier: Expr9921
• Subcellular Localization: The observed GFP signal was distributed diffusely within cells and spared the nucleus, suggesting that CBS-1 is localized in the cytoplasm.

9 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
seventh pharyngeal muscle cell layer	pm7	m7	WBbt:0003721
eighth pharyngeal muscle cell layer (single cell)	pm8	lineage name: MSaaapapp	WBbt:0004302
third pharyngeal muscle cell layer	pm3	M3	WBbt:0003740
fifth pharyngeal muscle cell layer	pm5	M5	WBbt:0003737
fourth pharyngeal muscle cell layer	pm4	M4	WBbt:0003739
sixth pharyngeal muscle cell layer	pm6	m6	WBbt:0003724

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00013866	cbs-1	ZC373.1	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024