WormMine: ExpressionPattern Expr2616

• Pattern: Expression of the reporter gene was observed in the touch cell AVM and its sister, the interneuron SDQR. A number of neurons in the head and tail regions were also observed to express the unc-2::GFP reporter gene. Neurons identified in the head included the olfactory sensory cells AWC. GFP expression was also observed in both the HSN and VC neurons. Cells expressing GFP in the tail region included the GABAergic neuron DVB. GFP fluorescence was found to be primarily localized within the nervous system. Expression was first observed late in embryogenesis at ~450 min of development when most neurons have been generated, and continued throughout development to the adult stage. GFP expression was observed only a subset of pharyngeal muscle cells but not in other types of muscle tissues. The unc-2 reporter gene was expressed in most motor neurons in the ventral nerve cord, nerve ring motoneurons-interneurons, and the touch cells.
• Primary Identifier: Expr2616

12 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
neurons that sense body touch, have specialized microtubules in processes.	touch receptor neuron	microtubule cell	WBbt:0005237
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNL	lineage name: ABplapppappa	WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNR	lineage name: ABprapppappa	WBbt:0004757
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWCL	lineage name: ABplpaaaaap	WBbt:0003827
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWCR	lineage name: ABprpaaaaap	WBbt:0003826
Ant. lateral interneuron, process projects into ring	SDQR	lineage name: QR.pap	WBbt:0004991
Neuron class of one sensory neuron, anterior ventral microtubule cell, touch receptor.	AVM	lineage name: QR.paa	WBbt:0003832
Neuron class of one ring interneuron, cell body in dorsorectal ganglion, inervates rectal muscles.	DVB	lineage name: K.p	WBbt:0004822
Posterior lateral interneuron, process projects into ring	SDQL	lineage name: QL.pap	WBbt:0004993

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006742	unc-2	T02C5.5	Caenorhabditis elegans

9 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018