WormMine: ExpressionPattern Expr11178

• Pattern: Expression of cwn-1 Wnt ligand decreases during aging. In very young adult worms, day 1 of adulthood, cwn-1/Wnt is expressed in body-wall muscles and ventral cord motor neurons in the posterior part of the worm. However, cwn-1/Wnt expression in body-wall muscles almost entirely disappears in the following 24 hours. By day 2 of adulthood we were able to observe only cwn-1 expression in ventral cord motor neurons. This expression is low in middle-age (day 5) worms, and barely detectable in old (day 12) animals. Overall the cwn-1/Wnt expression pattern is similar to that previously observed during development. In addition to body-wall muscles and ventral cord motor neurons, cwn- 1/Wnt was detected in intestinal cells, vulval muscle, and fused seam cells during larvae development (Gleason et al. 2006), although this expression pattern is absent in adulthood.
• Primary Identifier: Expr11178

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000857	cwn-1	K10B4.6	Caenorhabditis elegans

0 Life Stages