WormMine: ExpressionPattern Expr1096

• Pattern: In early embryos and until the lima bean stage, LET-413 was ubiquitously expressed. As development proceeds, expression became restricted to epithelial cells, and was stronger in the epidermis and the pharynx than in the intestine. Throughout larval development and in adults LET-413GFP was detected in epidermal seam cells, the pharynx, the rectum, the excretory pore, and more weakly in the intestine. Expression was also detected in epithelial tissues contributing to the reproductive system: the vulva, the uterus and the spermatheca. In addition to this epithelial expression, LET-413 was detected in the nerve ring.
• Primary Identifier: Expr1096
• Subcellular Localization: LET-413 is always associated with membranes. LET-413::GFP was uniformly localized along the basolateral membrane, but was not detected in the apical membrane in any epithelial tissue. Within the limits of resolution of confocal microscopy, the apical-most boundary of the LET-413 expression domain in the epidermis and the pharynx appeared to partially overlap with adherens junctions.

14 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
an accordion-like tube that contains sperm and is the site of oocyte fertilization.	spermatheca		WBbt:0005319
The passageway in the hindgut between the posterior intestine, the rectal valve and the opening to the exterior.	rectum		WBbt:0005773
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
cell that makes up epithelium in pharynx.	pharyngeal epithelial cell	pharyngeal epithelium	WBbt:0005459
adult vulval toroid cell, F, formed by fusion of precursors of lineage names P6.papl, P6.papr, P6.ppal and P6.ppar.	vulF		WBbt:0006768
adult vulval toroid cell, E, formed by fusion of precursors of lineage names P6.paal, P6.paar, P6.pppl and P6.pppr.	vulE		WBbt:0006767
The outlet of the excretory sinus to the exterior environment through the cuticle, on the ventral side of the head, just behind the nerve ring.	excretory pore	pore	WBbt:0005778
adult vulval toroid cell, C, formed by fusion of precursors of lineage names P5.ppal, P5.ppar, P7.papl and P7.papr.	vulC		WBbt:0006765
adult vulval toroid cell, D, formed by fusion of precursors of lineage names P5.ppp and P7.paa.	vulD		WBbt:0006766
adult vulval toroid cell, B2.	vulB2		WBbt:0006764
adult vulval toroid cell, B1, formed by fusion of precursors of lineage names P5.papa and P7.ppap.	vulB1		WBbt:0006763
adult vulval toroid cell, A, formed by fusion of precursors of lineage names P5.paaa, P5.paap, P7.pppa and P7.pppp	vulA		WBbt:0006762
toroidal epithelial cell that make up the bulk of the uterus, four cells anterior and four cells posterior to the vulva.	uterine toroidal epithelial cell	ut cell	WBbt:0006784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002632	let-413	F26D11.11	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002