WormMine: ExpressionPattern Expr12480

• Pattern: GFP fluorescence in animals carrying the unc-23::gfp construct is found throughout development appearing first at the 1.5-fold stage of embryogenesis in a few unidentified cells. Expression of the GFP-tagged UNC-23 protein continues during embryogenesis and by the 3-fold stage, it has expanded to include muscle, hypodermal and pharyngeal cells. In adult hermaphrodites GFP fluorescence is expressed in the pharynx, body wall muscle cells, hypodermis, vulva, and H cells, as well as some unidentified neurons and touch cells. In the hypodermis, UNC-23::GFP is distributed throughout the entire tissue including some nuclei and nucleoli, and in addition, is localized in a pattern reminiscent of the intermediate filaments. In body wall muscle cells, UNC-23::GFP is localized to the dense bodies and M lines in a pattern similar to that observed for several proteins including PAT-3/b-integrin, UNC-112, UNC-97/ PINCH, and PAT-4/ILK.
• Primary Identifier: Expr12480

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
female genital.	vulva		WBbt:0006748
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
neurons that sense body touch, have specialized microtubules in processes.	touch receptor neuron	microtubule cell	WBbt:0005237
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Contractile cell that makes up muscle tissue.	muscle cell		WBbt:0003675
	pharyngeal cell		WBbt:0005460
primary cell type that forms the hypodermis.	hypodermal cell		WBbt:0007846
Head lateral ectoblast which gives rise to hypodermal cells in the head.	H cell		WBbt:0008596

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006760	unc-23	H14N18.1	Caenorhabditis elegans

4 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019