WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Staining was first evident in 1.5-fold embryos and although the spatial expression was dynamic, stained neuronal and non-neuronal cells were also observed at later embryonic stages. In larvae and adults, ALR-1 expression was observed in multiple neuronal and non-neuronal cells (including epidermal cells) in the head, neuronal cells in the tail and in the GABAergic DD and VD motoneurons (MNs) in the ventral nerve cord. ALR-1 expression was observed in 24 of 26 GABAergic neurons, including the 13 VD and 6 DD, and the RME L/R, AVL, RIS and DVB neurons throughout postembryonic development. Primary Identifier  Expr3487
Remark  No staining was observed in alr-1(oy42) mutants. Subcellular Localization  Consistent with ALR-1 being a transcription factor, expression was exclusively nuclear in all observed cell types.

7 Anatomy Terms

Definition Name Synonym Primary Identifier
Neuron class of six motoneurons, with cell bodies in the ventral cord, which innervate dorsal muscles. Each cell has a short, posteriorly directed and a longer, anteriorly directed process emanating from its cell body. The anterior process has a branch, which leaves the ventral cord as a commissure and runs round to the dorsal cord. DD neuron   WBbt:0005270
Neuron class of thirteen motoneurons, with cell bodies in the ventral cord, which innervate ventral muscles. Each cell has an anteriorly directed process emanating from its cell body. VD neuron   WBbt:0005303
Neuron class of one ring interneuron, cell body in dorsorectal ganglion, inervates rectal muscles. DVB lineage name: K.p WBbt:0004822
Neuron class of one ring and ventral cord interneuron, few synapses. AVL lineage name: ABprpappaap WBbt:0003843
Ring motor neuron RMER lineage name: ABalaaaarrp WBbt:0005023
Neuron class of one ring interneuron. RIS lineage name: ABprpappapa WBbt:0005045
Ring motor neuron RMEL lineage name: ABalaaaarlp WBbt:0005025

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00044330 alr-1 R08B4.2 Caenorhabditis elegans

9 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo. fully-elongated embryo Ce WBls:0000021
  The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. 3-fold embryo Ce WBls:0000020
  The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo. 1.5-fold embryo Ce WBls:0000018
  The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo. 2-fold embryo Ce WBls:0000019