WormMine: ExpressionPattern Expr10991

• Pattern: elt-1 reporter gene expression was first seen around the 20-30 cell stage and was maintained during subsequent early embryogenesis in cells corresponding to hypodermal precursor cells. Just prior to morphogenesis, reporter gene expression could be seen in all the major hypodermal cell nuclei. During formation of the comma stage, embryo reporter gene expression declined in the dorsal and ventral hypodermis but remained high in the lateral seam cells. The seam-cell expression of the reporter gene continued throughout morphogenesis to the pretzel stage although at lower levels. In addition, at the threefold stage of development high levels of expression were seen in a group of cells adjacent to the pharynx in a position consistent with neuronal cells of the retrovesicular ganglion. During postembryonic development relatively low levels of expression were maintained in seam cells from the L1 to the adult stage as were high levels of ELT-1 in neuronal cells of the retrovesicular ganglion. ELT-1 expression was also clearly apparent in several different groups of neuronal cell bodies and axons; those of the ventral cord were the most prominent. Expression was also seen in several neurons in which the axon extended from the ventral cord and encircled the pharynx just in front of the posterior bulb.The reporter gene also showed postembryonic expression in sex-specific structures. In hermaphrodites, ELT-1 expression was seen in the vulval muscles (vm1 and vm2) and in males, in a subset of the lateral seam, the SET cells, that give rise to the sensory rays.
• Primary Identifier: Expr10991

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
seam cell in male tail; does not fuse with main seam, does not make alae.	male tail seam cell	male posterior seam	WBbt:0006912
primary cell type that forms the hypodermis.	hypodermal cell		WBbt:0007846
neuron whose cell body is in the retrovesicular ganglion.	retrovesicular ganglion neuron	retrovesicular ganglion	WBbt:0005403
Set one type of vulval muscle.	vm1	vulval muscle, type 1	WBbt:0006917
Set two type of vulval muscle.	vm2	vulval muscle, type 2	WBbt:0006918

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001249	elt-1	W09C2.1	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002