WormMine: ExpressionPattern Expr7986

• Pattern: cwn-1 was first observed in early embryos, at approximately 0-2 hours after egg laying. cwn-1 expression persisted throughout embryonic development. Baugh et al. previously showed that cwn-1 was expressed in embryonic body wall muscles derived from the C and D blastomeres. Throughout larval development cwn-1 is expressed in body wall muscles (BWMs) and ventral cord neurons (VCNs), predominately in the posterior half of the animal. In the L1 and L2 stages, cwn-1::GFP is expressed predominantly posterior to P6.p, although some animals show expression in the area of the VPCs. During the L3 and L4 stages, the domain of cwn-1 expression expands to more anterior BWMs and VCNs. Expression of cwn-1 was also observed in intestinal nuclei, and in nuclei of hypodermal cells that had joined the hyp7 syncytium, such as the VPC descendants and progeny from seam cell lineages. In late L4 and young adult animals, expression of cwn-1 was observed in the vulval muscles and in fused seam cells.
• Primary Identifier: Expr7986
• Remark: Picture: Figure 2, Figure S3.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000857	cwn-1	K10B4.6	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003