WormMine: ExpressionPattern Expr11629

• Pattern: Pcwn-2::mCherry signal first appeared in the intestine before the expression of Punc-25::GFP during embryogenesis. At late embryonic stage when RMED/V neurite start extending posteriorly, the highest expression of CWN-2 is found at posterior pharyngneal bulb and the pharyngeal-intestinal valve. When animals are at L1 stage, the RMED/V neurites grow towards the posterior pharynx, where CWN-2 displays relatively higher expression level. The expression pattern of CWN-2 at both embryonic and L1 stages correlates well with the attractant role of CWN-2 during neurite outgrowth. After L1 stage, the neurites continue their growth and pass the posterior pharynx; meanwhile CWN-2 is also found expressed in body muscles and some ventral cord neurons.
• Primary Identifier: Expr11629
• Remark: Temporal description.

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Ring motor neuron	RMED	lineage name: ABalapppaap	WBbt:0005027
Ring motor neuron	RMEV	lineage name: ABplpappaaa	WBbt:0005021
the last, posterior bulb of the pharynx.	terminal bulb		WBbt:0003732

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000858	cwn-2	W01B6.1	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023