WormMine: ExpressionPattern Expr8717

• Pattern: The strongest signals appeared late in embryogenesis and in L1 animals, coinciding with unc-7 mRNA levels, and UNC-7::GFP was detected in all motor neuron classes in the vental nerve cord; in older larvae expression was seen in all post-embryonically derived motor neuron classes (VA, VB, AS, VD, and VC).
• Primary Identifier: Expr8717
• Remark: Picture: Figure 4C. UNC-7::GFP expression mirrored that observed with anti-UNC-7 antibodies. However, some cell bodies could now be recognized with variability, probably due to over-expression from the rescuing array. Because in these animals UNC-7L::GFP expression was not detected by western blot analysis, authors attribute the majority of this signal to UNC-7S::GFP and conclude that UNC-7S is broadly expressed in many interneurons and motor neurons.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
Neuron class of thirteen motoneurons, with cell bodies in the ventral cord, which innervate ventral muscles. Each cell has an anteriorly directed process emanating from its cell body.	VD neuron		WBbt:0005303
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339
Neuron class of eleven motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VB neuron		WBbt:0005336
Neuron class of eleven motoneurons, with cell bodies in the ventral cord, which innervate dorsal muscles.	AS neuron		WBbt:0005334
Neuron class of six motoneurons in the ventral cord, which innervate ventral body muscles and the vm2 muscles of the vulva.	VC neuron		WBbt:0005304

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006747	unc-7	R07D5.1	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021