WormMine: ExpressionPattern Expr944

• Pattern: GFP is found in the body wall, vulval, spermathecal, uterine, and anal sphincter/depressor muscles. A few unidentified cells also exhibit GFP expression, suggesting that UNC-112 may not be limited to contractile tissues.
• Primary Identifier: Expr944
• Subcellular Localization: In the body wall muscle, UNC-112::GFP is localized to muscle cell boundaries in regions of contact with adjacent muscle cells, and to the dense bodies and M-lines in a pattern identical to that observed for UNC-52/perlecan, PAT-3/ -integrin, and PAT-2/ -integrin (Williams, B., unpublished observations). GFP fluorescence appears to localize near the membrane and does not extend very deeply into the muscle cell. In embryos, the UNC-112::GFP protein first localizes to regions of cell-cell contact between adjacent muscle cells, and then spreads over the muscle cell basal surface as the embryo elongates. In a 1.5-fold embryo, UNC-112::GFP appears as a single thin line in each quadrant, corresponding to the line of contact formed between the two rows of muscle cells.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
an accordion-like tube that contains sperm and is the site of oocyte fertilization.	spermatheca		WBbt:0005319
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
a single, H-shaped cell which lies just above the anus and connects the roof of the anal canal to the dorsal bodywall; its contractions act to increase the size of the anal opening by lifting the roof of the rectum and hence facilitate expulsion of intestinal contents.	anal depressor muscle	dilator muscle	WBbt:0004292
a saddle-shaped muscle cell that encircles the intestinal-rectal valve	anal sphincter muscle	lineage name: ABprpppppap	WBbt:0005798
muscle lining of the uterine wall.	uterine muscle		WBbt:0005342

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006836	unc-112	C47E8.7	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003