WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Expression observed in most or all neurons at high levels as well as in some hypodermal and muscle cells. In most neurons, sax-3::GFP expression is transient, peaking during the period of axon outgrowth. Highest level of expression is observed in the embryo, particularly during the initial period of axon outgrowth at 350-400 min (comma-stage). At comma-stage high level of expression is observed in anterior embryo, including most developing neurons of the nerve ring and a swath of ventral cells that includes the developing motor neurons of the ventral nerve cord and posterior neurons such as PVQ. Lower level of expression is observed in the epidermal cells. 200-400 - cell stage; 200-300 min of development: Expression seen in all epidermal cells at low level. 3-fold stage; >500 min of development: Expression seen in muscles that extend from nerve ring to the anterior tip of the head. L1: Expression in motor neurons in the head including RMD, RMG, SMD, SIA and SIB neurons; projection interneurons in the head and tail, including AVA, AVB, PVC, AVD, PVQ and ALA neurons; and the sensory OLQ neuron. This neuronal expression diminishes throughout postembryonic development. During L1, expression persists in the head muscles and appears in muscles along the body wall, with ventral muscles expressing more strongly than posterior muscles. This expression continues until the adult stage. Epidermal expression was rarely seen in larval stages. L2: Expression observed in HSN motor neurons. HSN motor neurons extends a growth cone (axon from their lateral cell bodies) towards the ventral midline and expression is at its highest at this point. L3: Expression observed in the axon reaching the ventral nerve cord. L4: Expression continues in HSN, when HSN axon grows anteriorly to the head. Adult: Expression decreases in HSN at this stage after the completion of HSN axon outgrowth. In addition expression observed in motor neurons, interneurons and sensory neurons listed above also postembryonic ventral cord motorneurons, some interneurons from the tail and head, body wall and vulval muscles. Primary Identifier  Expr716
Remark  This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).
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36 Anatomy Terms

Definition Name Synonym Primary Identifier
Epidermal layer. hypodermis epidermis WBbt:0005733
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion. body wall musculature body muscle WBbt:0005813
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. neuron neurone WBbt:0003679
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNL lineage name: ABplapppappa WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNR lineage name: ABprapppappa WBbt:0004757
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCL lineage name: ABplpppaapaa WBbt:0004094
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCR lineage name: ABprpppaapaa WBbt:0004092
Interneuron, projects along ventral cord to ring PVQL lineage name: ABplapppaaa WBbt:0004076
Interneuron, projects along ventral cord to ring PVQR lineage name: ABprapppaaa WBbt:0004074
Neuron class of one neuron, sends processes laterally and along dorsal cord. ALA lineage name: ABalapppaaa WBbt:0003955
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDVR lineage name: ABarappppaa WBbt:0004969
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDDR lineage name: ABprpapaaaa WBbt:0004971
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDVL lineage name: ABalppappaa WBbt:0004970
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBVR lineage name: ABprpapaapp WBbt:0004977
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDDL lineage name: ABplpapaaaa WBbt:0004972
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBDL lineage name: ABplppaaaaa WBbt:0004981
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha AVAL lineage name: ABalppaaapa WBbt:0003870
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha AVAR lineage name: ABalaappapa WBbt:0003869
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBDR lineage name: ABprppaaaaa WBbt:0004979
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBVL lineage name: ABplpapaapp WBbt:0004978
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta. AVBR lineage name: ABprpaapaap WBbt:0003867
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIAVL lineage name: ABplpapappa WBbt:0004985
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIAVR lineage name: ABprpapappa WBbt:0004983
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIADR lineage name: ABprpapaapa WBbt:0004987
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta. AVBL lineage name: ABplpaapaap WBbt:0003868
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIADL lineage name: ABplpapaapa WBbt:0004989
Quadrant outer labial neuron OLQVL lineage name: ABplpaaappaa WBbt:0004437
Quadrant outer labial neuron OLQVR lineage name: ABprpaaappaa WBbt:0004431
Quadrant outer labial neuron OLQDL lineage name: ABalapapapaa WBbt:0004439
Quadrant outer labial neuron OLQDR lineage name: ABalapppapaa WBbt:0004438

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004729 sax-3 ZK377.2 Caenorhabditis elegans

8 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation. gastrulating embryo Ce WBls:0000010
  The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. 3-fold embryo Ce WBls:0000020
  The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo. comma embryo Ce WBls:0000017