WormMine: ExpressionPattern Expr13241

• Pattern: In contrast to UNC-44C::GFP, we did not detect expression of UNC-44L::GFP(ju1412) before the bean stage of embryogenesis. By the 1.5-fold stage of embryogenesis, we observed expression of UNC-44L::GFP mainly in the developing nervous system. UNC-44L::GFP became progressively more concentrated in the nervous system, predominantly localizing to neuronal processes and to the peripheries of neuronal cell bodies. UNC-44L has been previously thought to be exclusively neuronal, based on immunostaining experiments. However, we observed faint expression of UNC-44L::GFP in epidermal seam cells at the L4 stage, and in the gonadal anchor cell at L3 stage, as well as in neighboring vulval cells at L4. Thus the regulation of UNC-44L is temporally and spatially distinct from the more widely expressed UNC-44 isoforms, and is predominantly but not exclusively confined to neurons.
• Primary Identifier: Expr13241

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal`s internal and external environments and to initiate and integrate its effector responses and activities.	nervous system		WBbt:0005735
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
anchor cell, induces vulva, part of hermaphrodite gonad.	anchor cell	AC	WBbt:0004522
Constituent cell of a hermaphrodite vulva.	vulval cell	vulval epithelial cell	WBbt:0007831

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006780	unc-44	B0350.2	Caenorhabditis elegans

8 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019