WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  A highly reproducible pattern of DKF-1 expression was observed as animals matured from embryo to adult. Intense fluorescence signals corresponding to DKF-1GFP revealed robust kinase accumulation in both (a) a region bounded by the anterior and posterior bulbs of the pharynx and (b) a tail area that contains lumbar, dorsorectal and pre-anal ganglia. Specifically, DKF-1 is differentially enriched in a cluster of cells that are immediately adjacent to the posterior pharyngeal bulb. Strong signals also emanate from cells positioned along the lateral surface of this bulb in animals carrying the dkf-1P::DKF-1GFP transgene. At the anterior pharyngeal bulb, DKF-1 accumulates selectively in bodies and in very thin processes (dendrites and axons) of two neurons. Nearly all cells expressing DKF-1 appear to be neurons. Two fluorescent cells with similar sizes and locations (at the anterior edge of the isthmusposterior bulb) may be M2 motor neurons. The location of the more posterior fluorescent neuron approximates the position of the cell body of an NSM neuron. DKF-1 also accumulates in a cell resembling I1. Other candidate DKF-1-enriched cells in the pharyngeal region include: the AWB, ADL, and ADF chemosensory neurons; and AVB and AIA interneurons.n C. elegans tail, DKF-1GFP expression is differentially elevated in neurons located within the dense neuropile of several tail ganglia. The pattern of fluorescence reveals that cell bodies and/or processes of phasmid neurons (PHA, PHB, and PHC), interneurons (PVC, DVA, DVB, PVQ, PVT) and motor neurons (VD13, DD6, VA12) are candidate sites for accumulation of DKF-1 protein. Primary Identifier  Expr7808
Remark  Picture: Figure 7. Subcellular Localization  Expressed in neuronal cell bodies and/or processes.
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32 Anatomy Terms

Definition Name Synonym Primary Identifier
Neuron class of one interneuron, projects along ventral cord to ring. PVT lineage name: ABplpappppa WBbt:0004070
Pharyngeal neurosecretory motorneuron, contain serotonin NSMR lineage name: ABaraapppaav WBbt:0004446
Pharyngeal neurosecretory motorneuron, contain serotonin NSML lineage name: ABaraapapaav WBbt:0004457
Amphid neuron, prob. chemosensory ADFL lineage name: ABalpppppaa WBbt:0004003
Amphid neuron, prob. chemosensory ADFR lineage name: ABpraaappaa WBbt:0003999
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWBL lineage name: ABalpppppap WBbt:0003829
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWBR lineage name: ABpraaappap WBbt:0003828
Interneuron, projects along ventral cord to ring PVQL lineage name: ABplapppaaa WBbt:0004076
Interneuron, projects along ventral cord to ring PVQR lineage name: ABprapppaaa WBbt:0004074
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCR lineage name: ABprpppaapaa WBbt:0004092
Amphid neuron, prob. chemosensory ADLL lineage name: ABalppppaad WBbt:0003997
Amphid neuron, prob. chemosensory ADLR lineage name: ABpraaapaad WBbt:0003995
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCL lineage name: ABplpppaapaa WBbt:0004094
Phasmid neurons, probably chemosensory PHAL lineage name: ABplpppaapp WBbt:0004366
Phasmid neurons, probably chemosensory PHAR lineage name: ABprpppaapp WBbt:0004365
Phasmid neurons, probably chemosensory PHBL lineage name: ABplapppappp WBbt:0004364
Phasmid neuron, probably chemosensory PHBR lineage name: ABprapppappp WBbt:0005659
Pharyngeal interneurons: ant sensory, input from RIP I1L lineage name: ABalpapppaa WBbt:0004746
Pharyngeal interneurons: ant sensory, input from RIP I1R lineage name: ABarapappaa WBbt:0004745
Neuron class of one ring interneuron, cell body in dorsorectal ganglion, has a large vesicle-filled process in ring. DVA lineage name: ABprppppapp WBbt:0004823
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta. AVBL lineage name: ABplpaapaap WBbt:0003868
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta. AVBR lineage name: ABprpaapaap WBbt:0003867
Neuron class of one ring interneuron, cell body in dorsorectal ganglion, inervates rectal muscles. DVB lineage name: K.p WBbt:0004822
Amphid interneuron AIAL lineage name: ABplppaappa WBbt:0003989
Amphid interneuron AIAR lineage name: ABprppaappa WBbt:0003987
Ventral cord motor neuron, innervates ventral body muscles, but also interneuron in preanal ganglion VA12 lineage name: P12.aaaa WBbt:0004645
Ventral cord motor neuron, innervates ventral body muscles, probably reciprocal inhibitor VD13 lineage name: P12.app WBbt:0004585
Pharyngeal motorneurons m2L lineage name: ABaraapappa WBbt:0004487
Pharyngeal motorneurons m2R lineage name: ABaraappppa WBbt:0004473
Neuron, striated rootlet in male, possibly sensory in tail spike PHCL lineage name: TL.pppaa WBbt:0004362

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00012352 dkf-1 W09C5.5 Caenorhabditis elegans

6 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003