WormMine: ExpressionPattern Expr16009

• Pattern: We found that ckr-1 is broadly expressed in the nervous system, showing expression in a subset of ventral nerve cord motor neurons, amphid and phasmid sensory neurons, premotor interneurons, and motor neurons in the nerve ring. We identified many of these neurons, largely from analysis of ckr-1 co-expression with previously characterized reporters. In the ventral nerve cord, we found that ckr-1 is expressed in cholinergic, but not GABAergic, ventral cord motor neurons. Amongst head neurons, the ckr-1 reporter is expressed in GABAergic RMEV, RMED, AVL and RIS neurons, cholinergic SMDV, SMDD, and RIV head motor neurons, the interneuron RIG, the serotonergic NSM neuron, and in the interneurons AIA and AIB. Additional studies using DiI uptake indicated that ckr-1 is also expressed in the amphid sensory neurons ASK and ASI and the phasmid sensory neurons PHA and PHB. With the exception of the ventral cord cholinergic neurons, the ckr-1 reporter almost exclusively labeled neurons that do not receive direct synaptic input from DVA, suggesting that NLP-12 acts at least partially through extrasynaptic mechanisms.
• Primary Identifier: Expr16009

32 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
Pharyngeal neurosecretory motorneuron, contain serotonin	NSML	lineage name: ABaraapapaav	WBbt:0004457
Pharyngeal neurosecretory motorneuron, contain serotonin	NSMR	lineage name: ABaraapppaav	WBbt:0004446
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASIR	lineage name: ABpraapapppa	WBbt:0003887
one member of amphid neurons, single ciliated ending, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASIL	lineage name: ABplaapapppa	WBbt:0003888
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASKL	lineage name: ABalpppapppa	WBbt:0003884
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASKR	lineage name: ABpraaaapppa	WBbt:0003883
Phasmid neurons, probably chemosensory	PHAL	lineage name: ABplpppaapp	WBbt:0004366
Phasmid neurons, probably chemosensory	PHAR	lineage name: ABprpppaapp	WBbt:0004365
neuron of phasmid sensillum	phasmid neuron		WBbt:0006753
neuron of the amphid sensillum	amphid neuron	amphid sensory neuron	WBbt:0005394
Phasmid neurons, probably chemosensory	PHBL	lineage name: ABplapppappp	WBbt:0004364
Phasmid neuron, probably chemosensory	PHBR	lineage name: ABprapppappp	WBbt:0005659
neuron that uses vesicular acetylcholine as a neurotransmitter.	cholinergic neuron	ACh neuron	WBbt:0006840
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDVR	lineage name: ABarappppaa	WBbt:0004969
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDR	lineage name: ABprpapaaaa	WBbt:0004971
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDVL	lineage name: ABalppappaa	WBbt:0004970
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDL	lineage name: ABplpapaaaa	WBbt:0004972
Neuron class of one ring and ventral cord interneuron, few synapses.	AVL	lineage name: ABprpappaap	WBbt:0003843
Ring motor neuron	RMED	lineage name: ABalapppaap	WBbt:0005027
Ring motor neuron	RMEV	lineage name: ABplpappaaa	WBbt:0005021
Neuron class of one ring interneuron.	RIS	lineage name: ABprpappapa	WBbt:0005045
Amphid interneuron	AIAR	lineage name: ABprppaappa	WBbt:0003987
Amphid interneuron	AIAL	lineage name: ABplppaappa	WBbt:0003989
	interneuron		WBbt:0005113
Amphid interneuron	AIBR	lineage name: ABpraapappa	WBbt:0003984
Amphid interneuron	AIBL	lineage name: ABplaapappa	WBbt:0003985
Ring interneuron	RIGR	lineage name: ABprppappaa	WBbt:0003930
Ring interneuron	RIGL	lineage name: ABplppappaa	WBbt:0003932
Ring interneuron	RIVR	lineage name: ABprpaapaaa	WBbt:0005041

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00020712	ckr-1	T23B3.4	Caenorhabditis elegans

0 Life Stages