WormMine: ExpressionPattern Expr1918

• Pattern: In the pAB::GFP fusion, expression was seen in some pioneering neurones of the nerve ring, beginning at the early comma stage. At the two-fold stage, expression was detected in some 10 neurones in the head that extend axons into the nerve ring, and in two neurones in the tail that extend processes anteriorly. This expression pattern was confirmed by immunohistochemistry with MAb 16-48-2. At the three-fold stage, expression was seen in all DA motoneurones and persisted while they pioneered the dorsal nerve chord. It was also seen in four to six neurones in each of the four head ganglia, including ALA and RID in the dorsal ganglion, and four of the six neurones of the terminal bulb, including M5. In the tail, two neurones in the pre-anal ganglion and six in the lumbar ganglion, including PVQL and PVQR, showed pAB::GFP expression. Additionally, a transient expression was seen in the four rows of bodywall muscle cells in the embryo. After hatching, in L1 larvae, the expression domain extended to amphid and phasmid socket cells, and subsequently in L2 larvae to all the newly born AS motoneurones. In hermaphrodite L3 larvae, expression was seen in the sex myoblasts subsequent to their anterior migration towards the position of the presumptive vulva, and in adult worms at a high level in the vulval muscles vm1 and vm2. In males, expression was seen in the diagonal and spicule retractor muscles.
• Primary Identifier: Expr1918

50 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
a saddle-shaped muscle cell that encircles the intestinal-rectal valve	anal sphincter muscle	lineage name: ABprpppppap	WBbt:0005798
Neuron class of one pharyngeal motorneuron.	M5 neuron	lineage name: MSpaaapap	WBbt:0004465
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
neuron making synapse on an effector (muscle, gland).	motor neuron	motoneuron	WBbt:0005409
Amphid socket cell, left	AMsoL	lineage name: ABplpaapapa	WBbt:0003931
Amphid socket cell, right	AMsoR	lineage name: ABprpaapapa	WBbt:0003929
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
Post-embryonic cell of pedigree TL.paa, phasmid sockets.	PHso1L	lineage name: TL.paa	WBbt:0004112
Post-embryonic cell of pedigree TR.paa. phasmid sockets.	PHso1R	lineage name: TR.paa	WBbt:0004110
Post-embryonic cell of pedigree TL.pap, phasmid sockets.	PHso2L	lineage name: TL.pap	WBbt:0004108
Post-embryonic cell of pedigree TR.pap, phasmid sockets.	PHso2R	lineage name: TR.pap	WBbt:0004106
Neuron class of one neuron, sends processes laterally and along dorsal cord.	ALA	lineage name: ABalapppaaa	WBbt:0003955
Neuron class of one ring motoneuron, projects along dorsal cord, innervates dorsal body muscle.	RID	lineage name: ABalappaapa	WBbt:0003938
	spicule retractor muscle		WBbt:0005827
ganglion in the head.	head ganglion		WBbt:0005135
The left and right lumbar ganglia lie behind the pre-anal ganglion in the tail, in lateral positions. Each contains 12 neuron cell bodies that send most of their neuronal processes into the ventral nerve cord via lumbar commissures and the pre-anal ganglion. There is no local neuropil in these ganglia in the hermaphrodite, instead they form most synapses in the pre-anal ganglion. Most lumbar neurons have sensory functions. In the adult male tail, these two ganglia gain many additional neurons and have some local neuropil. The lumbar neurons lie in close association with the lateral hypodermis, and most are posterior to the anus.	lumbar ganglion	lumbar lateral ganglia	WBbt:0005830
ganglion anterior to the anus.	preanal ganglion		WBbt:0005448
Ventral cord motor neurons, innervate dorsal muscles	DA2	lineage name: ABplppapapa	WBbt:0004869
Ventral cord motor neurons, innervate dorsal muscles	DA6	lineage name: ABplpppaaap	WBbt:0004861
Ventral cord motor neurons, innervate dorsal muscles	DA7	lineage name: ABprpppaaap	WBbt:0004859
Ventral cord motor neurons, innervate dorsal muscles	DA3	lineage name: ABprppapapa	WBbt:0004867
Ventral cord motor neurons, innervate dorsal muscles	DA4	lineage name: ABplppapapp	WBbt:0004865
Ventral cord motor neurons, innervate dorsal muscles	DA5	lineage name: ABprppapapp	WBbt:0004863
specialized muscle in the male.	diagonal muscle	dgl	WBbt:0005815
Vulval muscle 1, of lineage M.vlpaaapp.	M.vlpaaapp	lineage name: M.vlpaaapp	WBbt:0004854
Vulval muscle 1, of lineage M.vlpaapaa.	M.vlpaapaa	lineage name: M.vlpaapaa	WBbt:0004853
Vulval muscle 1, of lineage M.vrpaaapp.	M.vrpaaapp	lineage name: M.vrpaaapp	WBbt:0004850
Vulval muscle 1, of lineage M.vrpaapaa.	M.vrpaapaa	lineage name: M.vrpaapaa	WBbt:0004849

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006788	unc-53	F45E10.1	Caenorhabditis elegans

10 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo.		comma embryo Ce	WBls:0000017
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018