WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Many cells, including the six touch receptor neurons, expressed green fluorescent protein (GFP) and b-galactosidase (LacZ) from mec-6 promoter and protein fusions. These fusions were expressed primarily in neurons (the six touch receptors, ventral cord motor neurons, HSN, PVD, PVC, IL1, and several other unidentified neurons near the nerve ring, in the anal ganglion and in the male tail sensory rays), muscles (the body wall, vulval, intestinal, anal depressor and sphincter muscles) and the excretory canal. Primary Identifier  Expr2261
Subcellular Localization  Cytoplasmic, but not extracellular, b-galactosidase has enzymatic activity. A full-length mec-6::lacZ fusion produced no b-galactosidase activity unless DNA encoding a synthetic transmembrane domain was added. The transmembrane domain-dependent changes in lacZ expression indicate that MEC-6 is a transmembrane protein with its C terminus situated extracellularly.
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59 Anatomy Terms

Definition Name Synonym Primary Identifier
neuron with cell body associated with the ventral nerve cord. ventral cord neuron ventral cord motoneuron WBbt:0005300
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion. body wall musculature body muscle WBbt:0005813
muscle associated with hermaphrodite vulva. vulval muscle   WBbt:0005821
a single, H-shaped cell which lies just above the anus and connects the roof of the anal canal to the dorsal bodywall; its contractions act to increase the size of the anal opening by lifting the roof of the rectum and hence facilitate expulsion of intestinal contents. anal depressor muscle dilator muscle WBbt:0004292
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
a saddle-shaped muscle cell that encircles the intestinal-rectal valve anal sphincter muscle lineage name: ABprpppppap WBbt:0005798
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNL lineage name: ABplapppappa WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNR lineage name: ABprapppappa WBbt:0004757
H-shaped cell associated with the excretory system, largest cell in C. elegans. excretory cell excretory canal cell WBbt:0005812
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. nerve ring circumpharyngeal nerve ring WBbt:0006749
Inner labial neuron IL1L lineage name: ABalapaappaa WBbt:0004553
Inner labial neuron IL1R lineage name: ABalaappppaa WBbt:0004551
intestinal muscle cell, attach to intestine and body wall anterior to anus intestinal muscle stomato-intestinal muscle WBbt:0005796
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCL lineage name: ABplpppaapaa WBbt:0004094
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta. PVCR lineage name: ABprpppaapaa WBbt:0004092
Neuron class of one neuron, posterior ventral microtuble cell, touch receptor. PVM lineage name: QL.paa WBbt:0004086
Anterior lateral microtubule cell, touch receptor ALML lineage name: ABarppaappa WBbt:0003954
Anterior lateral microtubule cell, touch receptor ALMR lineage name: ABarpppappa WBbt:0003953
Neuron class of one sensory neuron, anterior ventral microtubule cell, touch receptor. AVM lineage name: QR.paa WBbt:0003832
Posterior lateral microtubule cell, touch receptor PLML lineage name: ABplapappppaa WBbt:0004104
Posterior lateral microtubule cell, touch receptor PLMR lineage name: ABprapappppaa WBbt:0004103
Post-embryonic cell of pedigree V6L.pppapaaa, male sensory rays, neuron, striated rootlet. R4AL lineage name: V6L.pppapaaa WBbt:0004030
Post-embryonic cell of pedigree V6R.pppapaaa, male sensory rays, neuron, striated rootlet. R4AR lineage name: V6R.pppapaaa WBbt:0004029
Post-embryonic cell of pedigree V6L.papapaaa, male sensory rays, neuron, striated rootlet. R2AL lineage name: R2L.aaa WBbt:0004042
Post-embryonic cell of pedigree V6R.papapaaa, male sensory rays, neuron, striated rootlet. R2AR lineage name: R2R.aaa WBbt:0004041
Neuron, lateral process adjacent to excretory canal PVDL lineage name: V5L.paapa WBbt:0004090
Neuron, lateral process adjacent to excretory canal PVDR lineage name: V5R.paapa WBbt:0004088
Post-embryonic cell of pedigree V6L.papppapa, male sensory rays, neuron, darkly staining tip, open to outside. R3BL lineage name: V6L.papppapa WBbt:0004034
Post-embryonic cell of pedigree V6R.papppapa, male sensory rays, neuron, darkly staining tip, open to outside. R3BR lineage name: V6R.papppapa WBbt:0004033
Post-embryonic cell of pedigree TL.appaaapa, male sensory rays, neuron, darkly staining tip, open to outside. R8BL lineage name: TL.appaaapa WBbt:0003990

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003170 mec-6 W02D3.3 Caenorhabditis elegans

0 Life Stages