WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  let-60 ras::lacZ. The Vulval lineage: First detected in L3 larvae (before vulval induction). Faint staining observed in P3.p-P8.p. Staining becomes stronger as VPCs begin dividing and fusion protein is expressed through adulthood. Faint staining observed in hyp7. Strong staining in vulA, vulB, vulC, vulD, vulE and vulF. Myoblast lineage: L1 (shortly after division of M) - Staining detected in M.d and M.v. Late L1, faint staining in progeny of M.v (body muscle) including SM (progeny of M.d (body muscle) ceases staining). L3: 8 progeny of SM (vulval muscle) stain before and after differentiation in muscle cells. Gonadal lineage: At hatching Z1 and Z4 gonadal cells stain. Progeny Z1 and Z4 that form distal tip cells (dtcs) and dtcs stain throughout larval development-adulthood. L4: Anchor cells (ac) of somatic gonad stains transiently at apex of invaginating vulva and continues until late L4 when ac nucleus fuses with uterine tissue. L4-adult expression (but not lacZ) Intense gfp near germline nuclei along border of distal arm of the gonad and in some places extended into the rachis. Muscle: L1-adult: All body wall muscle cells stain. Pharyngeal muscle pmp3-8 begin staining in L1 and continue until adulthood. Hypodermis: Begin staining in L2-3 larvae but consistent staining does not occur until the L4 stage and continues until adulthood. Hypodermal cells staining include V and H lineage-derived seam cells and V and H derived lateral hypodermal cells. Ventral hypodermal cells derived from P lineage also stain weakly but consistently in the adult. Intestine: Intestinal cells of late L1 larvae stain briefly during their terminal division. No staining after L2. Nervous system and excretory cells: extensive staining but not entirely at hatching throughout development. Beginning L1 - adulthood: Many ventral cord neurons stain positively identified include FLPL,R AVKL,R and either AIMR or AIYR based on co-staining with an anti-FMRF amide and an anti-galactosidase antibody. Nucleus of excretory cell stains in L1 to adulthood. Primary Identifier  Expr689
Remark  Reporter gene fusion type not specified. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).

40 Anatomy Terms

Definition Name Synonym Primary Identifier
neuron with cell body associated with the ventral nerve cord. ventral cord neuron ventral cord motoneuron WBbt:0005300
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion. body wall musculature body muscle WBbt:0005813
muscle associated with hermaphrodite vulva. vulval muscle   WBbt:0005821
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad anterior distal tip cell gon herm dtc A WBbt:0004520
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad posterior distal tip cell gon herm dtc P WBbt:0004506
Amphid interneuron AIYR lineage name: ABprpapaaap WBbt:0003961
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail seam cell lateral hypodermis WBbt:0005753
entire syncytium of hyp7 hyp7 syncytium hyp7 WBbt:0005734
Ring interneuron AIMR lineage name: ABprpaapppa WBbt:0003969
  excretory system   WBbt:0005736
  P6.p hermaphrodite   WBbt:0008125
descendent cell of post-embryonic blast cell P5, posterior, in hermaphrodite. P5.p hermaphrodite   WBbt:0008121
descendent cell of post-embryonic blast cell P4, posterior, in hermaphrodite. P4.p hermaphrodite   WBbt:0008117
descendent cell of post-embryonic blast cell P3, posterior in hermaphrodite. P3.p hermaphrodite   WBbt:0008112
  P8.p hermaphrodite   WBbt:0008133
  P7.p hermaphrodite   WBbt:0008129
adult vulval toroid cell, F, formed by fusion of precursors of lineage names P6.papl, P6.papr, P6.ppal and P6.ppar. vulF   WBbt:0006768
adult vulval toroid cell, E, formed by fusion of precursors of lineage names P6.paal, P6.paar, P6.pppl and P6.pppr. vulE   WBbt:0006767
anchor cell, induces vulva, part of hermaphrodite gonad. anchor cell AC WBbt:0004522
seventh pharyngeal muscle cell layer pm7 m7 WBbt:0003721
organ producing either sperm or ova. gonad   WBbt:0005175
adult vulval toroid cell, C, formed by fusion of precursors of lineage names P5.ppal, P5.ppar, P7.papl and P7.papr. vulC   WBbt:0006765
adult vulval toroid cell, D, formed by fusion of precursors of lineage names P5.ppp and P7.paa. vulD   WBbt:0006766
adult vulval toroid cell, B2. vulB2   WBbt:0006764
adult vulval toroid cell, B1, formed by fusion of precursors of lineage names P5.papa and P7.ppap. vulB1   WBbt:0006763
adult vulval toroid cell, A, formed by fusion of precursors of lineage names P5.paaa, P5.paap, P7.pppa and P7.pppp vulA   WBbt:0006762
eighth pharyngeal muscle cell layer (single cell) pm8 lineage name: MSaaapapp WBbt:0004302
third pharyngeal muscle cell layer pm3 M3 WBbt:0003740
fifth pharyngeal muscle cell layer pm5 M5 WBbt:0003737
fourth pharyngeal muscle cell layer pm4 M4 WBbt:0003739

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002335 let-60 ZK792.6 Caenorhabditis elegans

5 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024