WormMine: ExpressionPattern Expr3776

• Pattern: In contrast, D1 and D2 were very strongly expressed in the muscles of the pharynx and vulva and in both the cell bodies and axons of a very restricted set of neurons. These included the hermaphrodite-specific neurons (HSNs), about four unidentified neurons with cell bodies in either the ventral or retrovesicular ganglion near the terminal bulb of the pharynx, and about six neurons with cell bodies in the lumbar ganglion in the tail, including PVQL and PVQR, as distinguished by their axonal patterning. A small number of axons were present in the nerve ring and the ventral cord. The lateral processes of ALNL and ALNR were also visible. D1 and D2 also exhibited sporadic and weak fluorescence in body wall and intestinal muscles. Isoform E was strongly expressed in the nervous system and was detected in the cell bodies and axons of most, if not all neurons, including those in the pharynx, and at least some of the neuron-associated sheath and/or socket cells. Isoform E was also observed in the excretory canals and the somatic gonad, including the spermatheca, gonadal sheath, and distal tip cells. Isoform B was expressed most strongly in the axons of neurons, particularly in the nerve ring and the ventral nerve cord. This pattern of expression was very similar to the staining pattern observed with UNC-73 B antibodies. UNC-73 B was also found more sporadically and at a lower level in anal depressor muscle, distal tip, P, seam, and developing vulva cells. Although C1 and C2/F were also expressed in axons, their expression was restricted to fewer neurons. Many process bundles within the body of the animal and neurons within the pharynx were positive for C1 and C2/F, but few axons were visible in the nerve ring. Along with the neuronal expression, C1 and C2/F were also expressed in neuron-associated socket and/or sheath cells and the neuroendocrine uv1 cells. A low level of expression was sporadically observed in body wall muscles.
• Primary Identifier: Expr3776
• Subcellular Localization: Expressed in axons and cell bodies.

34 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
An interfacial epithelial cell which forms a distal cap on a sheath cell to bind the sheath of a sensillum to the neighboring hypodermis, via adherens junctions. There is often a narrow opening through the socket from the exterior into the sheath channel, allowing ciliated dendrites to be exposed to the external environment. The socket cell functions similarly to a glial cell.	socket cell		WBbt:0005750
female genital.	vulva		WBbt:0006748
an accordion-like tube that contains sperm and is the site of oocyte fertilization.	spermatheca		WBbt:0005319
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNL	lineage name: ABplapppappa	WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNR	lineage name: ABprapppappa	WBbt:0004757
a structural (glial) cell which forms an specialized environment surrounding the sensory ending(s) of one or more neurons; sometimes accompanied by a more distal socket cell. In early development of the sensory nerves and of the nerve ring some sheath cells (cephalics and labials) may also provide a substrate for axon guidance	neuronal sheath cell	pocket cell	WBbt:0005811
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
intestinal muscle cell, attach to intestine and body wall anterior to anus	intestinal muscle	stomato-intestinal muscle	WBbt:0005796
Four processes (canals) of the excretory canal cell each contain a central collecting lumen which feeds to a central lumenal canal in the cell body; the central canal forms a specialized membrane to release fluids into the excretory duct. These five canals form a continuous H-shaped channel which extends almost the full length of the body, generally in contact with the lateral hypodermis and the pseudocoelom.	excretory canal	canal	WBbt:0005775
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
The tenth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P10		WBbt:0006779
The ninth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P9		WBbt:0006778
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P11	lineage name: ABplapappa	WBbt:0004410
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P12	lineage name: ABprapappa	WBbt:0004409
uterine-vulval cell proximal to the vulva.	uv1		WBbt:0006791
five pairs of thin gonadal sheath cells form a single layer covering the germ line component of each arm, each pair occupying a stereotyped position along the gonad proximal-distal axis.	gonadal sheath cell		WBbt:0005828
The sixth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P6		WBbt:0006775
The fifth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P5		WBbt:0006774
The fourth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P4		WBbt:0006773
The third (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P3		WBbt:0006772
The eighth (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P8		WBbt:0006777
The seventh (count from anterior-most) of twelve postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1.	P7		WBbt:0006776

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006805	unc-73	F55C7.7	Caenorhabditis elegans

0 Life Stages