WormMine: ExpressionPattern Expr12601

• Pattern: sox-2 expression is restricted to subsets of neuroblasts. sox-2 is expressed relatively late in nervous system development, in the progenitor of differentiated neurons, but not in earlier neuroectodermal cells. sox-2 is also expressed in some progenitors of non-neural tissue, in the head hypodermis and the arcade cells. sox-2 is expressed in several postembryonic blast cells that are generated in the embryo. These blast cells include the B, Y, F, U and K rectal epithelial cells and the seam cells along the body. Although expression of sox-2 is absent in the terminal neurons generated by these lineages, sox-2 expression extends beyond the blast cell stage [e.g. sox-2 expression is maintained in the V5 daughters (V5a and V5p) but is lost in the next division].sox-2 is expressed in the sensory neurons AWB, AWC, IL1, IL2, URA, URB, OLL, the interneurons AIM, AIN, AVK, RIH and the motor neuron class RME. The sox-2 fosmid reporter or sox-2 smFISH did not show any expression in the germ line or oocytes of young adult worms. Expression patterns obtained by smFISH were very similar to the ones observed with fosmid reporters.
• Primary Identifier: Expr12601

50 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
Interfacial (hypodermal) cells which connect the hypodermal epithelium of the lips to the pharyngeal epithelium, firmly binding the inner tissue (the pharynx) to the outer bodywall (the hypodermis).	arcade cell		WBbt:0005793
Inner labial neuron	IL1VR	lineage name: ABarapppppaa	WBbt:0004547
Inner labial neuron	IL1DR	lineage name: ABalappppaaa	WBbt:0004737
Inner labial neuron	IL1L	lineage name: ABalapaappaa	WBbt:0004553
Inner labial neuron	IL1R	lineage name: ABalaappppaa	WBbt:0004551
Inner labial neuron	IL1VL	lineage name: ABalppapppaa	WBbt:0004549
Inner labial neuron	IL1DL	lineage name: ABalapappaaa	WBbt:0004738
A blast cell from which a neuron develops.	neuroblast		WBbt:0008594
Ring interneuron	AIML	lineage name: ABplpaapppa	WBbt:0003983
Ring interneuron	AIMR	lineage name: ABprpaapppa	WBbt:0003969
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWBR	lineage name: ABpraaappap	WBbt:0003828
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWBL	lineage name: ABalpppppap	WBbt:0003829
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWCL	lineage name: ABplpaaaaap	WBbt:0003827
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWCR	lineage name: ABprpaaaaap	WBbt:0003826
Ring motor neuron	RMER	lineage name: ABalaaaarrp	WBbt:0005023
Ring motor neuron	RMED	lineage name: ABalapppaap	WBbt:0005027
Ring motor neuron	RMEV	lineage name: ABplpappaaa	WBbt:0005021
Ring motor neuron	RMEL	lineage name: ABalaaaarlp	WBbt:0005025
Lateral outer labial neurons	OLLL	lineage name: ABalppppapaa	WBbt:0004445
Lateral outer labial neurons	OLLR	lineage name: ABpraaapapaa	WBbt:0004444
Rectal cell, postembryonic blast cell in male	B cell	lineage name: ABprppppapa	WBbt:0003825
Rectal cell, blast cell in male	F cell	lineage name: ABplppppapp	WBbt:0004799
Ring and ventral cord interneuron.	AVKR	lineage name: ABprpapapap	WBbt:0003844
Ring and ventral cord interneuron.	AVKL	lineage name: ABplpapapap	WBbt:0003845
Inner labial neuron	IL2VR	lineage name: ABarapppppp	WBbt:0004537
Inner labial neuron	IL2DR	lineage name: ABalappppap	WBbt:0004543
Inner labial neuron	IL2L	lineage name: ABalapaappp	WBbt:0004541
Inner labial neuron	IL2R	lineage name: ABalaappppp	WBbt:0004539
Inner labial neuron	IL2VL	lineage name: ABalppapppp	WBbt:0004538

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004949	sox-2	K08A8.2	Caenorhabditis elegans

0 Life Stages